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Proceedings Paper

Progress in the noninvasive in-vivo tissue-modulated Raman spectroscopy of human blood
Author(s): Joseph Chaiken; William F. Finney; Xiaoke Yang; Paul E. Knudson; Karen P. Peterson; Charles M. Peterson; Ruth S. Weinstock; Douglas Hagrman
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Paper Abstract

We have recently presented the first Raman spectra of in vivo human blood. A brief review of how to obtain such spectra and normalize them to the appropriate blood volume is given showing how to produce spectra that can be used for noninvasive quantitative analysis of blood in vivo. New clinical data from individuals and groups completely reproduce and extend all the earlier results. These new data reveal how certain small differences between individuals result in some variability in their noninvasive quantitation. We show the origin of this variability and how to obtain quantitative corrections based entirely on the individual measurement and tabulated data.

Paper Details

Date Published: 4 June 2001
PDF: 12 pages
Proc. SPIE 4254, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III, (4 June 2001); doi: 10.1117/12.427936
Show Author Affiliations
Joseph Chaiken, Syracuse Univ., Laser Chemical Corp., and LighTouch Medical Inc. (United States)
William F. Finney, Syracuse Univ. (United States)
Xiaoke Yang, LighTouch Medical Inc. (United States)
Paul E. Knudson, SUNY Upstate Medical Univ. and VA Medical Ctr. (United States)
Karen P. Peterson, LighTouch Medical Inc. (United States)
Charles M. Peterson, LighTouch Medical Inc. (United States)
Ruth S. Weinstock, SUNY Upstate Medical Univ. and VA Medical Ctr. (United States)
Douglas Hagrman, LighTouch Medical (United States)


Published in SPIE Proceedings Vol. 4254:
Biomedical Diagnostic, Guidance, and Surgical-Assist Systems III
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron, Editor(s)

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