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Proceedings Paper

Radio frequency tumor ablation: improving therapeutic efficacy with combined therapies
Author(s): S. Nahum Goldberg
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Paper Abstract

Radiofrequency (RF) tumor ablation has been demonstrated as a reliable method for creating thermally induced coagulation necrosis using either a percutaneous approach with image-guidance or direct surgical placement of thin electrodes into tissues to be treated. Early clinical trials with this technology have studied the treatment ofhepatic, cerebral, and bony malignancies. More recently this technology has been used to treat a host of malignant processes throughout the body. However, limitations in the technique and tumor biophysiology prevent optimal treatment of all desired lesions. Hence, investigators are studying combined methods of tumor destruction using RF ablation and adjuvant therapies that can modulate tumor biophysiology. These include using agents to alter tissue conductivity and blood flow, as well as combining RE with chemotherapy. Recent results using the combination therapy approach will be discussed.

Paper Details

Date Published: 1 June 2001
PDF: 12 pages
Proc. SPIE 4247, Thermal Treatment of Tissue: Energy Delivery and Assessment, (1 June 2001); doi: 10.1117/12.427868
Show Author Affiliations
S. Nahum Goldberg, Beth Israel Deaconess Medical Ctr./Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 4247:
Thermal Treatment of Tissue: Energy Delivery and Assessment
Thomas P. Ryan, Editor(s)

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