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Proceedings Paper

Excimer laser lead extraction catheter with increased laser parameters
Author(s): M. Sean Coe; Kevin D. Taylor; Rebecca A. Lippincott; Oleg Sorokoumov M.D.; Thanassis Papaioannou
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Paper Abstract

A fiber optic catheter connected to a pulsed excimer laser (308 nm) is currently used to extract chronically implanted pacemaker and defibrillator leads at Fluence of 60 mJ/mm2 and repetition rate of 40 Hz. The object of this study was to determine the effect of higher repetition rates (80 Hz) in the catheter's cutting performance. The penetration rate (micrometers /sec), and the associated mechanical and thermal effects were measured in soft (porcine myocardium) and hard tissue (bovine tendon) at 60 mJ/mm2-80 Hz, and were compared to the corresponding values at commercially available laser parameters (60 mJ/mm2-40 Hz). Ablation rates were measured with perforation experiments and the extent of thermal and mechanical damage was measured under polarized light microscopy. For hard (soft) tissue, the laser catheter demonstrated penetration speed of 106 +/- 32 (302 +/- 101) micrometers /sec at 40 Hz and 343 +/- 120 (830 +/- 364) micrometers /sec at 80 Hz. Maximum extent of thermal effects at 40 Hz and 80 Hz was 114 +/- 35 micrometers (72 +/- 18) and 233 +/- 63 micrometers (71 +/- 16) respectively. Maximum extent of mechanical effects at 40 Hz and 80 Hz was 188 +/- 63 micrometers (590 +/- 237) and 386 +/- 100 micrometers (767 +/- 160) respectively. In vitro testing of the laser catheter with 80 Hz laser parameters has demonstrated increased penetration speed in both soft and hard fibrous tissue, while maintaining associated thermal and mechanical effects within limited ranges.

Paper Details

Date Published: 21 May 2001
PDF: 7 pages
Proc. SPIE 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI, (21 May 2001); doi: 10.1117/12.427834
Show Author Affiliations
M. Sean Coe, Spectranetics Corp. (United States)
Kevin D. Taylor, Spectranetics Corp. (United States)
Rebecca A. Lippincott, Spectranetics Corp. (United States)
Oleg Sorokoumov M.D., Cedars-Sinai Medical Ctr. (United States)
Thanassis Papaioannou, Cedars-Sinai Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 4244:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI
Lawrence S. Bass M.D.; David S. Robinson M.D.; Eugene A. Trowers M.D.; Kenton W. Gregory M.D.; Lou Reinisch; Kenneth Eugene Bartels D.V.M.; R. Rox Anderson M.D.; Reza S. Malek M.D.; Kenneth Eugene Bartels D.V.M.; Lloyd P. Tate V.D.M.; Abraham Katzir; C. Gaelyn Garrett M.D.; Timothy A. Woodward M.D.; Hans-Dieter Reidenbach; George M. Peavy D.V.M.; Lawrence S. Bass M.D.; C. Gaelyn Garrett M.D.; Michael D. Lucroy D.V.M.; Kenton W. Gregory M.D.; Abraham Katzir; Nikiforos Kollias; Michael D. Lucroy D.V.M.; Reza S. Malek M.D.; J. Stuart Nelson M.D.; George M. Peavy D.V.M.; Hans-Dieter Reidenbach; Lou Reinisch; David S. Robinson M.D.; Lloyd P. Tate V.D.M.; Eugene A. Trowers M.D.; Timothy A. Woodward M.D., Editor(s)

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