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Proceedings Paper

Large-area polymer replication for microfluidic devices
Author(s): Mathias Heckele; Andreas Gerlach; Andreas E. Guber; Thomas Schaller
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Paper Abstract

A huge market development is expected for modern drug discovery and genomic analysis when rapid parallel analysis of a large number of samples gets available at affordable costs. The state of the art shows that low cost devices can be fabricated in mass production by micromolding of polymers. In close collaboration, Greiner Bio-One and Forschungszentrum Karlsruhe have developed a single-use plastic microfluidic capillary electrophoresis (CE) array in the standardized microplate footprint. This paper presents the results of experiences which show that hot embossing with a mechanically micromachined molding tool is the appropriate technology for low cost mass fabrication. A subsequent sealing of the microchannels allows sub-microliter sample volumes in 96- channel multiplexed microstructures.

Paper Details

Date Published: 5 April 2001
PDF: 9 pages
Proc. SPIE 4408, Design, Test, Integration, and Packaging of MEMS/MOEMS 2001, (5 April 2001); doi: 10.1117/12.425380
Show Author Affiliations
Mathias Heckele, Forschungszentrum Karlsruhe GmbH (Germany)
Andreas Gerlach, Greiner Bio-One (Germany)
Andreas E. Guber, Forschungszentrum Karlsruhe GmbH (Germany)
Thomas Schaller, Forschungszentrum Karlsruhe GmbH (Germany)


Published in SPIE Proceedings Vol. 4408:
Design, Test, Integration, and Packaging of MEMS/MOEMS 2001
Bernard Courtois; Jean Michel Karam; Steven Peter Levitan; Karen W. Markus; Andrew A. O. Tay; James A. Walker, Editor(s)

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