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Proceedings Paper

Compact endoscopic fluorescence detection system for gastrointestinal cancers
Author(s): Valerie Nadeau; Miles J. Padgett; Jacqueline Hewett; Wilson Sibbett; Khaled Hamdan; Sami Mohammed; Iain Tait; Alfred Cushieri
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Paper Abstract

We describe a compact endoscopic imaging system for the detection of gastro-intestinal cancers. This system is designed to image ALA-induced PpIX fluorescence and allows the clinician to perform fluorescence endoscopy and white light endoscopy simultaneously. The system comprises a filtered mercury arclamp for illumination and fluorescence excitation, a dual camera system coupled to an endoscope for detection and a desktop PC for processing and display of images. The result is a real-time colour image onto which fluorescence information is superimposed. Preliminary in vivo results indicate an increased fluorescence level within cancers in comparison with normal tissue. In addition, the system allows point spectroscopy to be carried out by the insertion of an optical fibre probe down the biopsy channel of the endoscope.

Paper Details

Date Published: 9 April 2001
PDF: 6 pages
Proc. SPIE 4248, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy X, (9 April 2001); doi: 10.1117/12.424440
Show Author Affiliations
Valerie Nadeau, Univ. of Glasgow (United Kingdom)
Miles J. Padgett, Univ. of Glasgow (United Kingdom)
Jacqueline Hewett, Univ. of St. Andrews (United Kingdom)
Wilson Sibbett, Univ. of St. Andrews (United Kingdom)
Khaled Hamdan, Ninewells Hospital and Medical School/Univ. of Dundee (United Kingdom)
Sami Mohammed, Ninewells Hospital and Medical School/Univ. of Dundee (United Kingdom)
Iain Tait, Ninewells Hospital and Medical School/Univ. of Dundee (United Kingdom)
Alfred Cushieri, Ninewells Hospital and Medical School/Univ. of Dundee (United Kingdom)


Published in SPIE Proceedings Vol. 4248:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy X
Thomas J. Dougherty, Editor(s)

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