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Proceedings Paper

Novel fabrication technique for development of polymer-based microsensor arrays for molecular diagnostics
Author(s): Paul Jacobs; Walter Hofer; Rudi Rossau; Wim Tachelet; Andrew Campitelli; Peter Detemple; Jeff Newman; Chris Flack; Andre Van de Voorde
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Paper Abstract

An innovative production technique is described for the low-cost production of arrays of interdigitated electrode (IDE) structures. The resulting polymer chips form the basis of a new type of diagnostic device allowing for the impedimetric detection of either hybridisation or immuno-affinity binding of antibody-antigen combinations. Sensitivity of the IDEs is maximised by focusing the field of sensitivity to the molecules of interest by lowering the electrode dimensions and spacing to the sub-micron region. This has been achieved using a unique combination of state-of-the-art micro-structuring of polymers and the directionality of metal-deposition by evaporation. Subsequently, polymer based arrays of IDEs with micron to sub-micron electrode widths can be realised using a single metallisation step, completely omitting any sophisticated photolithography.

Paper Details

Date Published: 21 March 2001
PDF: 7 pages
Proc. SPIE 4235, Smart Structures and Devices, (21 March 2001); doi: 10.1117/12.420851
Show Author Affiliations
Paul Jacobs, Innogenetics, NV (Belgium)
Walter Hofer, Innogenetics, NV (Belgium)
Rudi Rossau, Innogenetics, NV (Belgium)
Wim Tachelet, Innogenetics, NV (Belgium)
Andrew Campitelli, IMEC (Belgium)
Peter Detemple, IMM GmbH (Germany)
Jeff Newman, Cranfield Biotechnology Ctr. (United Kingdom)
Chris Flack, Biodot Ltd. (United Kingdom)
Andre Van de Voorde, Innogenetics, NV (Belgium)


Published in SPIE Proceedings Vol. 4235:
Smart Structures and Devices
Dinesh K. Sood; Ronald Albert Lawes; Vasundara V. Varadan, Editor(s)

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