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Proceedings Paper

Stereotactic use of the 980-nm diode laser in rat cortical and subcortical tissues
Author(s): Murat Guelsoy; Tansu Celikel; Ozlem Kurtkaya; Aydin Sav; Adnan Kurt; Resit Canbeyli; Inci F. Cilesiz
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Paper Abstract

The use of 980 nm diode laser irradiation within cortical tissue was investigated by the author's previous work. In the present study the lesions created in cortical and subcortical tissues and lesioning effects of diode laser applied in continuous and pulsed regimes were compared. In vivo stereotaxic neurosurgical procedure was performed on female Wistar rats' cortical and subcortical tissues. 980 nm diode laser was applied in two different regimes, cw and pulsed wave respectively. Lesion dimensions were measured and compared. The lasing parameters were found suitable for both brain regions. No significant difference was found between tissues. Lesions diameters varied in the range of 1.0-9.0 mm. Histological examination revealed data for a limited thermal damage in the surrounding tissue for all lesions. Cortical and subcortical tissues did not show significant differences due to same amount of energy delivered. The lasing regime did not influence the dimensions of lesions. Applied energy was found the key element determining the amount of lesion. Results were consistent with the findings found in the previous dosimetry studies.

Paper Details

Date Published: 31 January 2001
PDF: 4 pages
Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); doi: 10.1117/12.413725
Show Author Affiliations
Murat Guelsoy, Bogazici Univ. (Turkey)
Tansu Celikel, Scuola Internazionale Superiore di Studi Avanzati (Turkey)
Ozlem Kurtkaya, Marmara Univ. (Turkey)
Aydin Sav, Marmara Univ. (Turkey)
Adnan Kurt, Teknofil Ltd. and Bogazici Univ. (Turkey)
Resit Canbeyli, Bogazici Univ. (Turkey)
Inci F. Cilesiz, Istanbul Technical Univ. (Turkey)

Published in SPIE Proceedings Vol. 4156:
Clinical Lasers and Diagnostics
Patrick Brouwer, Editor(s)

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