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Proceedings Paper

Efficiency of autofluorescence diagnosis and photodynamic therapy (PDT) of bladder tumors: our own experience
Author(s): Michal Szygula; Boguslaw Wojciechowski; Aleksander Sieron; Mariusz Adamek; Wojciech Cebula; Tomasz Biniszkiewicz; Witold Zieleznik; Aleksandra Kawczyk-Krupka
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Paper Abstract

The efficiency of autofluorescence diagnosis within urinary bladder was analyzed in the study. We examined two groups of patients: the first one consisting of 22 patients suspected to have bladder cancer and the second one consisting of 45 patients who have undergone transurethral electro resection due to urinary bladder neoplasms. Our goal was to detect cancerous tissue invisible in white-light examination. In the first group sensitivity was 100 percent and specificity was 69.23 percent. In the second group sensitivity was 96 percent and specificity was 80 percent. We also report in the study treatment efficiency of PDT in 12 patients with superficial bladder cancer. In our procedure two hours after the instillation of bladder with ALA solution, the lesion was irradiated by laser light. In 9 out of 12 treated patients regression of bladder tumor was obtained, while in 3 cases a progression of neoplasmatic process was observed.

Paper Details

Date Published: 31 January 2001
PDF: 7 pages
Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); doi: 10.1117/12.413704
Show Author Affiliations
Michal Szygula, Silesian Medical Univ. (Poland)
Boguslaw Wojciechowski, Silesian Medical Univ. (Poland)
Aleksander Sieron, Silesian Medical Univ. (Poland)
Mariusz Adamek, Silesian Medical Univ. (Poland)
Wojciech Cebula, Silesian Medical Univ. (Poland)
Tomasz Biniszkiewicz, Silesian Medical Univ. (Poland)
Witold Zieleznik, Silesian Medical Univ. (Poland)
Aleksandra Kawczyk-Krupka, Silesian Medical Univ. (Poland)

Published in SPIE Proceedings Vol. 4156:
Clinical Lasers and Diagnostics
Patrick Brouwer, Editor(s)

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