Share Email Print
cover

Proceedings Paper

Promising cancer treatment modality: the University of California Davis/McClellan Nuclear Radiation Center neutron capture therapy program
Author(s): Susan A. Autry-Conwell; James E. Boggan; Benjamin F. Edwards; Yongjin Hou; Maria-Graca Vincente; Hungyuan Liu; Wade J. Richards
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Neutron capture therapy (NCT) is a promising new binary therapeutic modality for the treatment of localized tumors. It is accomplished by injection and localization within the tumor of a neutron capture agent (NCA) that alone, is non- toxic. Whenthe tumor is then exposed to neutrons, a relatively non-toxic form of radiation, crytotoxic products are produced that directly or indirectly cause tumor cell death, and yet preserves normal surrounding tissue not contain the NCA. The UC Davis NCT program is currently working to develop and test new compounds or NCA in vitro and in vivo. Many groups worldwide are also working to develop the next generation NCA, but less than five facilities internationally are currently capable to treating clinical brain tumor patients by NCT and only two US facilities, MIT and Brookhaven National Laboratory. In addition to compound development, the UC Davis NCT program is preparing the UC Davis McClellan Nuclear Radiation Center's 2 megawatt TRIGA reactor for NCT clinical trials which would make it the only such facility on the West Coast.

Paper Details

Date Published: 18 December 2000
PDF: 4 pages
Proc. SPIE 4142, Penetrating Radiation Systems and Applications II, (18 December 2000); doi: 10.1117/12.410584
Show Author Affiliations
Susan A. Autry-Conwell, Univ. of California Davis (United States)
James E. Boggan, Univ. of California Davis (United States)
Benjamin F. Edwards, Univ. of California Davis (United States)
Yongjin Hou, Univ. of California Davis (United States)
Maria-Graca Vincente, Univ. of California Davis (United States)
Hungyuan Liu, Univ. of California Davis and Univ. of California Davis/McClellan Nuclear Radiation Ctr. (United States)
Wade J. Richards, Univ. of California Davis/McClellan Nuclear Radiation Ctr. (United States)


Published in SPIE Proceedings Vol. 4142:
Penetrating Radiation Systems and Applications II
F. Patrick Doty; H. Bradford Barber; Hans Roehrig; Edward J. Morton, Editor(s)

© SPIE. Terms of Use
Back to Top