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Proceedings Paper

Integrated CT-SPECT system for small-animal imaging
Author(s): Mark Bennett Williams; Guimin Zhang; Mitali J. More; Allen R. Goode; Stan Majewski; Randy F. Wojcik; Brian Kross; Vladimir Popov; Andrew G. Weisenberger; Martin J. Stanton; Walter Charles Phillips; Alexander X. Stewart; Thomas G. McCauley; Tao Wu; Edward V.R. DiBella
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Paper Abstract

We are developing a scanner for simultaneous acquisition of x-ray computed tomography (CT) and single photon emission tomography (SPECT) images of small animals such as mice and rats. The scanner uses a cone beam geometry for both the x- ray transmission and gamma emission projections by using an area x-ray detector and pinhole collimator, respectively. The CT and SPECT data set are overlaid to form a coregistered structural-functional 3D image. The CT system includes a single CCD-based x-ray detector and a microfocus x-ray source. The SPECT scanner utilizes tungsten pinhole collimators and arrays of CsI(Tl) scintillation detectors. We describe considerations and the early performance of a prototype scanner.

Paper Details

Date Published: 18 December 2000
PDF: 10 pages
Proc. SPIE 4142, Penetrating Radiation Systems and Applications II, (18 December 2000); doi: 10.1117/12.410571
Show Author Affiliations
Mark Bennett Williams, Univ. of Virginia (United States)
Guimin Zhang, Univ. of Virginia (United States)
Mitali J. More, Univ. of Virginia (United States)
Allen R. Goode, Univ. of Virginia (United States)
Stan Majewski, Thomas Jefferson National Accelerator Facility (United States)
Randy F. Wojcik, Thomas Jefferson National Accelerator Facility (United States)
Brian Kross, Thomas Jefferson National Accelerator Facility (United States)
Vladimir Popov, Thomas Jefferson National Accelerator Facility (United States)
Andrew G. Weisenberger, Thomas Jefferson National Accelerator Facility (United States)
Martin J. Stanton, Brandeis Univ. (United States)
Walter Charles Phillips, Brandeis Univ. (United States)
Alexander X. Stewart, Brandeis Univ. (United States)
Thomas G. McCauley, Brandeis Univ. (United States)
Tao Wu, Brandeis Univ. (United States)
Edward V.R. DiBella, Univ. of Utah (United States)


Published in SPIE Proceedings Vol. 4142:
Penetrating Radiation Systems and Applications II
F. Patrick Doty; H. Bradford Barber; Hans Roehrig; Edward J. Morton, Editor(s)

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