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Proceedings Paper

Cancer diagnostics by infrared spectroscopy
Author(s): Martina Meinke; Ingo H. Gersonde; Uwe Bindig; Markus Mueller; Kurt Miller; Gerhard J. Mueller
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Paper Abstract

A diagnostic method to detect differences between diseased and normal tissue from bladder carcinoma by FTIR-microspectroscopy is described. Regions of interest on 10 micrometer thin tissue sections where mapped in transmission mode. After IR-Mapping, the samples have been analyzed with common pathological techniques. Quadratic discriminant as well as correlation analysis was applied to the obtained IR-maps allowing differentiation between cancerous and normal tissue. In the case of the correlation analyses it is further possible to distinguish between different types of tissue.

Paper Details

Date Published: 16 November 2000
PDF: 9 pages
Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); doi: 10.1117/12.409331
Show Author Affiliations
Martina Meinke, Universitaetsklinikum Charite/Humboldt Univ. zu Berlin (Germany)
Ingo H. Gersonde, Laser-und Medizin-Technologie Berlin GmbH (Germany)
Uwe Bindig, Laser-und Medizin-Technologie Berlin GmbH (Germany)
Markus Mueller, Universitaetsklinikum Benjamin Franklin der Freie Univ. Berlin (Germany)
Kurt Miller, Universitaetasklinikum Benjamin Franklin der Freie Univ. Berlin (Germany)
Gerhard J. Mueller, ILMTB and Universitaetsklinikum Benjamin Franklin (Germany)


Published in SPIE Proceedings Vol. 4161:
Optical Biopsy and Tissue Optics
Irving J. Bigio; Gerhard J. Mueller; Gerwin J. Puppels; Rudolf W. Steiner; Katarina Svanberg, Editor(s)

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