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Proceedings Paper

Laser-induced fluorescence spectroscopy (LFS): detection of unstable thrombogenic atherosclerotic plaque formation in a rabbit model: a first-look diagnostic approach
Author(s): Alexander M. Christov; Erbin Dai; Maria Drangova; Liying Liu; George S. Abela; Piers Nash; Grant McFadden; Alexandra Lucas
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Paper Abstract

Many approaches to imaging of unstable plaque have been applied to detect vascular thrombosis and occlusion with only moderate success. LFS detected significant and specific changes in thrombogenic plaque in a rabbit model. Fluorescence emission intensity analysis of structural characteristics may provide an optical diagnostic technique for early recognition of unstable coronary syndromes.

Paper Details

Date Published: 16 November 2000
PDF: 12 pages
Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); doi: 10.1117/12.409329
Show Author Affiliations
Alexander M. Christov, Univ. of Western Ontario (United States)
Erbin Dai, Univ. of Western Ontario (Canada)
Maria Drangova, Univ. of Western Ontario (Canada)
Liying Liu, Univ. of Western Ontario (Canada)
George S. Abela, Michigan State Univ. (United States)
Piers Nash, Univ. of Western Ontario (Canada)
Grant McFadden, Univ. of Western Ontario (Canada)
Alexandra Lucas, Univ. of Western Ontario (Canada)


Published in SPIE Proceedings Vol. 4161:
Optical Biopsy and Tissue Optics
Irving J. Bigio; Gerhard J. Mueller; Gerwin J. Puppels; Rudolf W. Steiner; Katarina Svanberg, Editor(s)

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