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Proceedings Paper

Laser diffractometry of erythrocyte deformation under hypo-osmotic hemolysis
Author(s): Stanislav S. Bessmeltsev; Alexander V. Lendiaev; Yulia A. Skvortsova; Vladimir Alexeevich Tarlykov
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Paper Abstract

The experimental research and theoretical modeling of average radius and refractive index change of spherocytes aggregation of ill and well people under the swelling in solutions of various osmolarity and by taking into account the rigidity of the erythrocyte membrane have been carried out. The spasmodic character of decrease of spherocyte radius has been discovered for the first time. It took place under an NaCl concentration on the order 0.50 - 0.35%. The correlation of the erythrocyte membrane rigidity with a 'jump' value and its position has been demonstrated. The experimental researches of the refractive index have confirmed the spasmodic model of change to the spherocyte radius.

Paper Details

Date Published: 27 November 2000
PDF: 6 pages
Proc. SPIE 4316, International Conference on Lasers for Measurements and Information Transfer, (27 November 2000); doi: 10.1117/12.407659
Show Author Affiliations
Stanislav S. Bessmeltsev, Research Institute of Hematology and Blood Transfusion (Russia)
Alexander V. Lendiaev, St. Petersburg Institute of Fine Mechanics and Optics (Russia)
Yulia A. Skvortsova, St. Petersburg Institute of Fine Mechanics and Optics (Russia)
Vladimir Alexeevich Tarlykov, St. Petersburg Institute of Fine Mechanics and Optics (Russia)


Published in SPIE Proceedings Vol. 4316:
International Conference on Lasers for Measurements and Information Transfer
Vadim E. Privalov, Editor(s)

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