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Proceedings Paper

Fluorescence spectrum of normal and carcinoma human lung tissue
Author(s): Changqing Yu; Yan Zhang; Haihua Song; Yi He; Jixiang Yan; Jiaze Li
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Paper Abstract

Laser-induced fluorescence (LIF) is a promising method for pre-malignant lung tissue diagnosis and it is very important to find effective common diagnosis criteria needed by clinic. In this paper, some differences between normal and cancer lung tissue, such as I444/I414 ratio, main peak width, and integral area were exhibited and discussed. By using the fourth harmonic at 266nm of a Q-switched Nd:YAG laser as an excitation source, Optical Multi-channel Analyzer (OMA) as a detector, laser-induced fluorescence spectra of normal and cancer lung tissue in-vitro were measured. According to the spectra characteristics, three independent diagnosis criteria were obtained and analyzed. The total specificity is above 95%.

Paper Details

Date Published: 11 October 2000
PDF: 4 pages
Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); doi: 10.1117/12.403992
Show Author Affiliations
Changqing Yu, Beijing Institute of Technology (China)
Yan Zhang, Beijing Institute of Technology (China)
Haihua Song, Beijing Institute of Technology (China)
Yi He, Beijing Institute of Technology (China)
Jixiang Yan, Beijing Institute of Technology (China)
Jiaze Li, Beijing Institute of Technology (China)

Published in SPIE Proceedings Vol. 4224:
Biomedical Photonics and Optoelectronic Imaging
Hong Liu; Qingming Luo, Editor(s)

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