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Proceedings Paper

Effect of morphine on PC12 cells with molecular radar
Author(s): Chen Shi; Xiaoli Yu; Jiuyi Lu; Chunyang Zhang; Lei Jin; Hui Ma; Dacheng Zhang; Die Yan Chen
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Paper Abstract

Molecular Radar (MR) is a new method to detect biological processes in living cells at the level of molecular, it is also the newest means to get intracellular information. In this paper we study the effect of morphine on PC12 cells using MR. The results show that the effect of morphine on PC12 cells is time- and concentration-dependent. Morphine treating for short time induces the increase and fluctuation of intracellular (CA2+), while morphine treating for long time induces chromatin condensation, loss of mitochondria membrane potential apoptosis.

Paper Details

Date Published: 11 October 2000
PDF: 5 pages
Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); doi: 10.1117/12.403977
Show Author Affiliations
Chen Shi, Tsinghua Univ. (China)
Xiaoli Yu, Peking Union Medical College (China)
Jiuyi Lu, Peking Union Medical College (China)
Chunyang Zhang, Tsinghua Univ. (China)
Lei Jin, Tsinghua Univ. (China)
Hui Ma, Tsinghua Univ. (China)
Dacheng Zhang, Peking Union Medical College (China)
Die Yan Chen, Tsinghua Univ. (China)


Published in SPIE Proceedings Vol. 4224:
Biomedical Photonics and Optoelectronic Imaging
Hong Liu; Qingming Luo, Editor(s)

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