Share Email Print

Proceedings Paper

Detection of glutamate in the eye by Raman spectroscopy
Author(s): Alvin Katz; Erik F. Kruger; Glenn Minko; C. H. Liu; Richard B. Rosen; Robert R. Alfano
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

In this work, Raman spectroscopy was investigated as a tool for monitoring glutamate levels in the eye. Glutamate is a by product of nerve cell death, and is an indicator of macular degeneration. Raman spectra was from ex vivo porcine eyes was investigated, with glutamate injected into the eyes to simulate disease conditions. The Raman spectra from the native eye was dominated by the lens. However, an optical system was designed to optimize collection of signal from the vitreous and reduce the background lens signal. The molecular signature of glutamate was detectable in the Raman spectra by this system.

Paper Details

Date Published: 29 September 2000
PDF: 3 pages
Proc. SPIE 4098, Optical Devices and Diagnostics in Materials Science, (29 September 2000); doi: 10.1117/12.401625
Show Author Affiliations
Alvin Katz, CUNY/City College (United States)
Erik F. Kruger, New York Eye and Ear Infirmary (United States)
Glenn Minko, CUNY/City College (United States)
C. H. Liu, CUNY/City College (United States)
Richard B. Rosen, New York Eye and Ear Infirmary (United States)
Robert R. Alfano, CUNY/City College (United States)

Published in SPIE Proceedings Vol. 4098:
Optical Devices and Diagnostics in Materials Science
David L. Andrews; David L. Andrews; Toshimitsu Asakura; Suganda Jutamulia; Wiley P. Kirk; Max G. Lagally; Ravindra B. Lal; James D. Trolinger, Editor(s)

© SPIE. Terms of Use
Back to Top