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Proceedings Paper

In-vivo noninvasive glucose monitoring with optical heterodyne polarimetry in a range of 50 mg/dl to 100 mg/dl
Author(s): Wei-Shing Wang; Chien-Yuan Han; Pei-Chin Tu; Chien Chou
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Paper Abstract

An amplitude sensitive optical heterodyne polarimeter was setup in order to monitor noninvasively the aqueous glucose concentration in rabbit's eye. A range of the blood glucose from 35 mg/dl to 135 mg/dl was measured in vivo by biological glucose assay (BGA), while the optional rotation of the aqueous glucose was measured by a polarimeter simultaneously. The experimental results showed the consistence between these two independent measurements. There was no time delay between the blood glucose and the aqueous glucose when the blood glucose was descending after the insulin was injected. It was in contract to a 10 minutes time delay when the blood glucose was ascending. The detection sensitivity of the polarimeter was 4 mg/dl in the measurement.

Paper Details

Date Published: 4 July 2000
PDF: 6 pages
Proc. SPIE 4082, Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications, (4 July 2000); doi: 10.1117/12.390545
Show Author Affiliations
Wei-Shing Wang, National Yang-Ming Univ. (Taiwan)
Chien-Yuan Han, National Yang-Ming Univ. (Taiwan)
Pei-Chin Tu, National Yang-Ming Univ. (Taiwan)
Chien Chou, National Yang-Ming Univ. (Taiwan)

Published in SPIE Proceedings Vol. 4082:
Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications
Robert R. Alfano; Peng Pei Ho; Arthur E. T. Chiou, Editor(s)

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