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Proceedings Paper

Development and application of noninvasive optical topography
Author(s): Tsuyoshi Yamamoto; Atsushi Maki; Yuichi Yamashita; Hiroshi Yoshizawa; Makoto Iwata; Eiju Watanabe; Yukari Tanikawa; Yukio Yamada; Hideaki Koizumi
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Paper Abstract

Optical tomography (OT) is a method for visualizing brain functions noninvasively. In an OT measurement system, near- infrared light, to which living tissue is highly permeable, is irradiated from the scale of the subject, and the scattered light reflected from the cerebral cortex is detected elsewhere on the scalp. The spatio-temporal blood volume change in the cortex is visualized based on the signal detected using two-dimensionally arranged optodes. The measurement imposes few constraints on the subject, either physically or mentally, thus the subject is in a natural and relaxed condition during measurement. Here we describe our OT system, then report on an experiment to evaluate the system using a phantom. We found that OT can accurately locate the activated region in the cortex. Also, as an example of a clinical application of OT, we used our system to measure the language function, demonstrating the system's ability to measure the activity of Broca's area.

Paper Details

Date Published: 4 July 2000
PDF: 10 pages
Proc. SPIE 4082, Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications, (4 July 2000); doi: 10.1117/12.390538
Show Author Affiliations
Tsuyoshi Yamamoto, Hitachi, Ltd. (Japan)
Atsushi Maki, Hitachi, Ltd. (Japan)
Yuichi Yamashita, Hitachi, Ltd. (Japan)
Hiroshi Yoshizawa, Tokyo Womens Medical Univ. (Japan)
Makoto Iwata, Tokyo Womens Medical Univ. (Japan)
Eiju Watanabe, Tokyo Metropolitan Police Hospital (Japan)
Yukari Tanikawa, Mechanical Engineering Lab. (Japan)
Yukio Yamada, Mechanical Engineering Lab. (Japan)
Hideaki Koizumi, Hitachi, Ltd. (Japan)

Published in SPIE Proceedings Vol. 4082:
Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications
Robert R. Alfano; Peng Pei Ho; Arthur E. T. Chiou, Editor(s)

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