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Proceedings Paper

Mutual information-based registration of cardiac ultrasound volumes
Author(s): Vladimir Zagrodsky; Raj Shekhar; J. Fredrick Cornhill
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Paper Abstract

Real-time volume ultrasound imaging of the heart is a new trend, and the registration of acquired volume framesets is clinically important. This registration may be accomplished by processing a selected pair of volume frames having identical cardiac phase (preferably end diastolic) from two framesets. The registration solves for the optimal rigid transformation between selected volumes through maximization of mutual information, a voxel similarity measure. The accuracy of registration was estimated through retrieval of an artificially introduced misalignment. Two volume frames, belonging to the same frameset and separated in time by 250 ms, were selected. The secondary volume was translated by seven voxels along each axis and rotated by seven degrees about each axis relative to the primary prior to registration. The translational mismatch upon registration was within one voxel and the rotational mismatch less than two degrees. Reduction of the speckle noise by spatio-temporal averaging followed by intensity binning was a key step in successful application of mutual information approach to ultrasound imaging. The application of our method to nine framesets arising from four different patients demonstrates the feasibility of using of mutual information for automatic registration of cardiac ultrasound data.

Paper Details

Date Published: 6 June 2000
PDF: 10 pages
Proc. SPIE 3979, Medical Imaging 2000: Image Processing, (6 June 2000); doi: 10.1117/12.387674
Show Author Affiliations
Vladimir Zagrodsky, Cleveland Clinic Foundation (United States)
Raj Shekhar, Cleveland Clinic Foundation (United States)
J. Fredrick Cornhill, Cleveland Clinic Foundation (United States)


Published in SPIE Proceedings Vol. 3979:
Medical Imaging 2000: Image Processing
Kenneth M. Hanson, Editor(s)

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