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Proceedings Paper

Computer-aided diagnosis system for lung cancer based on retrospective helical CT image
Author(s): Yuji Ukai; Noboru Niki; Hitoshi Satoh; Kenji Eguchi; Kiyoshi Mori; Hironobu Ohmatsu; Ryutaro Kakinuma; Masahiro Kaneko; Noriyuki Moriyama
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Paper Abstract

In this paper, we present a computer-aided diagnosis (CAD) system for lung cancer to detect nodule candidates at an early stage from the present and the early helical CT screening of the thorax. We developed an algorithm that can compare automatically the slice images of present and early CT scans for the assistance of comparative reading in retrospect. The algorithm consists of the ROI detection and shape analysis based on comparison of each slice image in the present and the early CT scans. The slice images of present and early CT scans are both displayed in parallel and analyzed quantitatively in order to detect the changes in size and intensity affection. We validated the efficiency of this algorithm by application to image data for mass screening of 50 subjects (total: 150 CT scans). The algorithm could compare the slice images correctly in most combinations with respect to physician's point of view. We validated the efficiency of the algorithm which automatically detect lung nodule candidates using CAD system. The system was applied to the helical CT images of 450 subjects. Currently, we are carrying out the clinical field test program using the CAD system. The results of our CAD system have indicated good performance when compared with physician's diagnosis. The experimental results of the algorithm indicate that our CAD system is useful to increase the efficiency of the mass screening process. CT screening of thorax will be performed by using the CAD system as a counterpart to the double reading technique actually used in herical CT screening program, not by using the film display.

Paper Details

Date Published: 6 June 2000
PDF: 12 pages
Proc. SPIE 3979, Medical Imaging 2000: Image Processing, (6 June 2000); doi: 10.1117/12.387607
Show Author Affiliations
Yuji Ukai, Univ. of Tokushima (Japan)
Noboru Niki, Univ. of Tokushima (Japan)
Hitoshi Satoh, Toshiba Corp. (Japan)
Kenji Eguchi, National Shikoku Cancer Ctr. Hospital (Japan)
Kiyoshi Mori, Togichi Cancer Ctr. (Japan)
Hironobu Ohmatsu, National Cancer Ctr. Hospital East (Japan)
Ryutaro Kakinuma, National Cancer Ctr. Hospital East (Japan)
Masahiro Kaneko, National Cancer Ctr. Hospital (Japan)
Noriyuki Moriyama, National Cancer Ctr. Hospital (Japan)


Published in SPIE Proceedings Vol. 3979:
Medical Imaging 2000: Image Processing
Kenneth M. Hanson, Editor(s)

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