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Proceedings Paper

Ex-vivo testing of crystalline lens substitutes: a pilot study
Author(s): Marie Hamaoui; Jean-Marie A. Parel; Fabrice Manns; Hassan Tahi; Arthur Ho; Brien Holden
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Paper Abstract

The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PARTM Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.

Paper Details

Date Published: 7 June 2000
PDF: 8 pages
Proc. SPIE 3908, Ophthalmic Technologies X, (7 June 2000); doi: 10.1117/12.387515
Show Author Affiliations
Marie Hamaoui, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine and Univ. of Miami (United States)
Jean-Marie A. Parel, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine and Univ. of Miami (United States)
Fabrice Manns, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine and Univ. of Miami (United States)
Hassan Tahi, Bascom Palmer Eye Institute/Univ. of Miami School of Medicine and Univ. of Liege (United States)
Arthur Ho, Univ. of New South Wales (Australia)
Brien Holden, Univ. of New South Wales (Australia)


Published in SPIE Proceedings Vol. 3908:
Ophthalmic Technologies X
Pascal O. Rol; Karen Margaret Joos M.D.; Fabrice Manns, Editor(s)

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