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Proceedings Paper

Investigation of the aggregation and disaggregation properties of erythrocytes by light-scattering measurements
Author(s): Juergen Lademann; Hans-Juergen Weigmann; Wolfram Sterry; Holger Kiesewetter; Andre Roggan; Gerhard J. Mueller; Alexander V. Priezzhev; Nikolai N. Firsov
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Paper Abstract

The aggregation and disaggregation behavior of erythrocytes reflects pathological states of the human body. The investigation of the aggregation and disaggregation process of human blood samples by laser spectroscopic measurements is described int he present paper. The whole blood samples were analyzed using a rotating coaxial cylinder system in combination with a special method for data processing. The erythrocyte aggregates were destroyed completely without injuring the cell membranes by shear forces arising during the cylinder rotation. The time behavior of the remission signal during the aggregation process was investigated. The disaggregation process was characterized by the dependence of the remission signal intensity on different applied shear rates.

Paper Details

Date Published: 31 May 2000
PDF: 6 pages
Proc. SPIE 3923, Optical Diagnostics of Biological Fluids V, (31 May 2000); doi: 10.1117/12.387142
Show Author Affiliations
Juergen Lademann, Universitatsklinikum Charite/Humboldt-Univ. Berlin (Germany)
Hans-Juergen Weigmann, Universitatsklinikum Charite/Humboldt-Univ. Berlin (Germany)
Wolfram Sterry, Universitatsklinikum Charite/Humboldt-Univ. Berlin (Germany)
Holger Kiesewetter, Universitatsklinikum Charite/Humboldt-Univ. Berlin (Germany)
Andre Roggan, Laser und Medizin Technologie gGmbH Berlin (Germany)
Gerhard J. Mueller, Laser und Medizin Technologie gGmbH Berlin (Germany)
Alexander V. Priezzhev, M.V. Lomonosov Moscow State Univ. (Russia)
Nikolai N. Firsov, Russian State Medical Univ. (Russia)

Published in SPIE Proceedings Vol. 3923:
Optical Diagnostics of Biological Fluids V
Alexander V. Priezzhev; Toshimitsu Asakura, Editor(s)

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