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Proceedings Paper

Possibility of quantitative estimation of blood cell forms by the spatial-frequency spectrum analysis
Author(s): Igor N. Spiridonov; Larisa P. Safonova; Andrey V. Samorodov
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Paper Abstract

At present in hematology there are no quantitative estimates of such important for the cell classification parameters: cell form and nuclear form. Due to the absence of the correlation between morphological parameters and parameters measured by hemoanalyzers, both flow cytometers and computer recognition systems, do not provide the completeness of the clinical blood analysis. Analysis of the spatial-frequency spectra of blood samples (smears and liquid probes) permit the estimate the forms quantitatively. On the results of theoretical and experimental researches carried out an algorithm of the form quantitative estimation by means of SFS parameters has been created. The criteria of the quality of these estimates have been proposed. A test bench based on the coherent optical and digital processors. The received results could be applied for the automated classification of ether normal or pathological blood cells in the standard blood smears.

Paper Details

Date Published: 31 May 2000
PDF: 7 pages
Proc. SPIE 3923, Optical Diagnostics of Biological Fluids V, (31 May 2000); doi: 10.1117/12.387137
Show Author Affiliations
Igor N. Spiridonov, Bauman Moscow State Technical Univ. (Russia)
Larisa P. Safonova, Bauman Moscow State Technical Univ. (Russia)
Andrey V. Samorodov, Bauman Moscow State Technical Univ. (Russia)

Published in SPIE Proceedings Vol. 3923:
Optical Diagnostics of Biological Fluids V
Alexander V. Priezzhev; Toshimitsu Asakura, Editor(s)

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