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Proceedings Paper

Peculiarities of lymph flow in microvessels
Author(s): Ekateryna I. Galanzha; Gregory E. Brill; Sergey S. Ulyanov; Valery V. Tuchin; Anastasiya V. Solov'eva; Alexey V. Sedykh
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Paper Abstract

In the present study the characteristics of lymph flow in microvessels are investigated in vivo by the speckle- interferometrical and biomicroscopic methods. Two parameters of the lymph flow velocity are determined. The first frequency-weighted spectral moment of Doppler signal (M1) was calculated. This parameter is proportional to lymph flow velocity. In the same regions of lymphatics the velocity of translational motion of the signal lymphocytes in the flow is assessed. The value of velocity and the parameter M1 essentially varied. The temporary dynamics of M1 indicated that the lymph flow had the alternating- translational character. Simultaneously the diameter of lymph microvessel, the amplitude and the rate of phasic contraction and the rate of valve functioning are registered. NG-nitro-L-arginine (L-NNA, 10-4 M), an inhibitor of nitric oxide synthase, is topically applied during 15 min. The application of L-NNA provoked the modulation of alternating-translational motion of lymph flow, the changes of diameters and rate of valve function and the stimulating of phasic contractions and the correlation between parameters of lymph microcirculation.

Paper Details

Date Published: 31 May 2000
PDF: 6 pages
Proc. SPIE 3923, Optical Diagnostics of Biological Fluids V, (31 May 2000); doi: 10.1117/12.387135
Show Author Affiliations
Ekateryna I. Galanzha, Saratov State Medical Univ. and Saratov State Univ. (Russia)
Gregory E. Brill, Saratov State Medical Univ. (Russia)
Sergey S. Ulyanov, Saratov State Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. and Mechanical Engineering Institute (Russia)
Anastasiya V. Solov'eva, Saratov State Medical Univ. (Russia)
Alexey V. Sedykh, Saratov State Univ. (Russia)

Published in SPIE Proceedings Vol. 3923:
Optical Diagnostics of Biological Fluids V
Alexander V. Priezzhev; Toshimitsu Asakura, Editor(s)

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