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Proceedings Paper

Molecular recognition of functionalized polydiacetylene and its biosensor
Author(s): Yajun Li; Yi Fan; Ligong Zhang; Shaojie Ma; Jiayin Zheng
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Paper Abstract

Molecular recognition processes are very important in the investigation of biological phenomena as well as development of fiber optic biosensor. As promising materials, biofunctionalized polydiacetylene lipids have many special properties. p-10,12-pentacosadiyne-1-N-(3,6,9- trioxaundecylanide)-a-D-mannopyranoside (MPDA) was synthesized from 10,12-pentacasadiynoic acid (PDA). The mixed monolayer MPDA/PDA was prepared by using Langmuir- Blodgett technique on glass and optical fiber, respectively. Molecular recognition of Escherichia coli (E. coli) resulted in a change of the film color and can be quantified by UV- Visible absorption spectroscopy. The properties might be used for screening drugs and diagnosis.

Paper Details

Date Published: 9 May 2000
PDF: 4 pages
Proc. SPIE 4077, International Conference on Sensors and Control Techniques (ICSC 2000), (9 May 2000); doi: 10.1117/12.385581
Show Author Affiliations
Yajun Li, Changchun Institute of Physics (China)
Yi Fan, Changchun Institute of Physics (China)
Ligong Zhang, Changchun Institute of Physics (China)
Shaojie Ma, Lab. of Excited State Processes (China)
Jiayin Zheng, East China Univ. of Science and Technology (China)

Published in SPIE Proceedings Vol. 4077:
International Conference on Sensors and Control Techniques (ICSC 2000)
Desheng Jiang; Anbo Wang, Editor(s)

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