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Proceedings Paper

Intraoral fiber-optic-based diagnostic for periodontal disease
Author(s): Bill W. Colston; Dora M. Gutierrez; Matthew J. Everett; Steve B. Brown; Kevin C. Langry; Weldon Royall Cox; Paul W. Johnson; Jeffrey N. Roe
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Paper Abstract

The purpose of this initial study was to begin development of a new, objective diagnostic instrument that will allow simultaneous quantitation of multiple proteases within a single periodontal pocket using a chemical fiber optic senor. This approach could potentially be adapted to use specific antibodies and chemiluminescence to detect and quantitate virtually any compound and compare concentrations of different compounds within the same periodontal pocket. The device could also be used to assay secretions in salivary ducts or from a variety of wounds. The applicability is, therefore, not solely limited to dentistry and the device would be important both for clinical diagnostics and as a research too.

Paper Details

Date Published: 3 May 2000
PDF: 8 pages
Proc. SPIE 3911, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II, (3 May 2000); doi: 10.1117/12.384906
Show Author Affiliations
Bill W. Colston, Lawrence Livermore National Lab. (United States)
Dora M. Gutierrez, Lawrence Livermore National Lab. (United States)
Matthew J. Everett, Lawrence Livermore National Lab. (United States)
Steve B. Brown, Lawrence Livermore National Lab. (United States)
Kevin C. Langry, Lawrence Livermore National Lab. (United States)
Weldon Royall Cox, MicroFab Technologies, Inc. (United States)
Paul W. Johnson, Univ. of California/San Francisco (United States)
Jeffrey N. Roe, Optical Focus Medical (United States)


Published in SPIE Proceedings Vol. 3911:
Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron, Editor(s)

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