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Proceedings Paper

Experimental and theoretical optimization of laser-produced x-ray spectra for vascular imaging
Author(s): Andrzej Krol; Zhiming Jiang; Zahia Ichalalene; Jean-Claude Kieffer; Charles C. Chamberlain; Ernest M. Scalzetti
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Paper Abstract

Experimental and theoretical studies of image quality using iodinated contrast agent and x-ray spectra generated by laser- based x-ray source were performed. A TableTop Terawatt (T3) laser (intensity: 1017 - 1019 W/cm-2, pulse duration: 150 fs or 450 fs, with or without controlled pre-pulse) was used to crate x-ray source. Infrared and/or green beams were utilized. Ba, La, Ce, Nd, and Gd laser targets were used. For each target, a number of suitable filters was utilized to produce optimized x-ray spectra for a specific imaging task. The MTF function due to the focal spot was obtained. A simple theoretical model of x-ray detector response was developed. An index of image quality (Detective Image Quality) as well as a figure of merit for dual energy imaging FOM(DESA) were defined and optimized via x-ray spectrum manipulation. The optimum, for a specific imaging task, technique parameters such as: target/filter combination, focal spot size, laser-light wavelength and surface power density, laser pulse duration, pre-pulse delay and contrast ratio, and hot electrons temperature were obtained experimentally and confirmed theoretically. We found that an optimized laser-based x-ray source can outperform conventional x-ray tube-based source in application to vascular imaging in terms of contrast resolution and spatial resolution.

Paper Details

Date Published: 25 April 2000
PDF: 11 pages
Proc. SPIE 3977, Medical Imaging 2000: Physics of Medical Imaging, (25 April 2000); doi: 10.1117/12.384507
Show Author Affiliations
Andrzej Krol, SUNY Upstate Medical Univ. at Syracuse (United States)
Zhiming Jiang, INRS-Energie et Materiaux (Canada)
Zahia Ichalalene, INRS-Energie et Materiaux (Canada)
Jean-Claude Kieffer, INRS-Energie et Materiaux (Canada)
Charles C. Chamberlain, SUNY Upstate Medical Univ. at Syracuse (United States)
Ernest M. Scalzetti, SUNY Upstate Medical Univ. at Syracuse (United States)

Published in SPIE Proceedings Vol. 3977:
Medical Imaging 2000: Physics of Medical Imaging
James T. Dobbins III; John M. Boone, Editor(s)

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