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Proceedings Paper

Dual-energy coronary angiography in pigs using a Gd contrast agent
Author(s): Stefan Fiedler; Helene Elleaume; Geraldine Le Duc; Christian Nemoz; Thierry Brochard; Michel Renier; Bernard Bertrand; Francois Esteve; Jean-Francois Le Bas; Pekka Suortti; William C. Thomlinson
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Paper Abstract

The European Synchrotron Radiation Facility Medical Research Beamline is now fully operational. One of the primary programs is the development of dual-energy transvenous coronary angiography for in vivo human research protocols. Previous work at this and other synchrotrons has been entirely devoted to the use of the dual-energy digital subtraction technique at the iodine k-absorption edge at 33.17 keV. The images are recorded in a line scan mode following venous injection of the contrast agent. Considerations of the patient dose, the dilution of the contrast agent in the pulmonary system and the arteries overlying the filled ventricles have limited the image quality. The ESRF facility was designed to allow dual- energy imaging at higher energies, for example at the gadolinium k-absorption edge at 50.24 keV. The advantages have been theoretically known for many years, with the higher energy promising higher image quality with less radiation dose. During the commissioning phase of the ESRF angiography program, the opportunity presented itself to image adult pigs in vivo with Gd contrast agent. This paper presents some initial results of the image quality in the Gd studies in comparison with iodine contrast agent studies, also carried out in adult pigs at the ESRF.

Paper Details

Date Published: 25 April 2000
PDF: 8 pages
Proc. SPIE 3977, Medical Imaging 2000: Physics of Medical Imaging, (25 April 2000); doi: 10.1117/12.384482
Show Author Affiliations
Stefan Fiedler, European Synchrotron Radiation Facility (France)
Helene Elleaume, Rayonnement Synchrotron et Recherche Medicale (France)
Geraldine Le Duc, European Synchrotron Radiation Facility (France)
Christian Nemoz, European Synchrotron Radiation Facility (France)
Thierry Brochard, European Synchrotron Radiation Facility (France)
Michel Renier, European Synchrotron Radiation Facility (France)
Bernard Bertrand, Rayonnement Synchrotron et Recherche Medicale (France)
Francois Esteve, Rayonnement Synchrotron et Recherche Medicale (France)
Jean-Francois Le Bas, Rayonnement Synchrotron et Recherche Medicale (France)
Pekka Suortti, Univ. of Helsinki (Finland)
William C. Thomlinson, European Synchrotron Radiation Facility (France)

Published in SPIE Proceedings Vol. 3977:
Medical Imaging 2000: Physics of Medical Imaging
James T. Dobbins; John M. Boone, Editor(s)

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