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Proceedings Paper

Volumetric monochromatic x-ray tomography of the lungs
Author(s): Cynthia B. Paschal; Frank Edward Carroll M.D.; John A. Worrell; Marcus H. Mendenhall; Robert H. Traeger; James W. Waters; Caryl N. Brzymialkiewicz; Gwen A. Banks
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Paper Abstract

Monochromatic x-rays were produced by inverse Compton scattering resolution from counter-propagation of a tunable free electron laser electron beam and its own infrared photon beam. In a manner analogous to electron beam CT, a mechanism was developed here for obtaining multiple projection views with monochromatic x-rays by deflecting x- rays off of mosaic crystals mounted on rotating stages. These crystals are both energy and angle selective. X-rays are detected digitally when they strike a phosphorescent screen mounted in front of a CCD camera. Using this system, multiple projection images of a 3D phantom and of rat lungs ex vivo were obtained. In an alternate micro-CT arrangement, rat lungs in situ were imaged by rotating the rat in front of both a polychromatic beam from a molybdenum target x-ray tube and the same beam monochromatized with a mosaic crystal. In the first arrangement, depth information was revealed by relative position changes of features seen in each projection and the approximately 0.16 mm thick walls of a catheter were visible in the images. Using conventional tomography, the projections were reconstructed into slice images. Overall, these monochromatic x-ray imaging methods offer reduced x-ray dose, the potential for improved contrast resolution, and now 3D information.

Paper Details

Date Published: 28 April 2000
PDF: 6 pages
Proc. SPIE 3925, Biomedical Applications of Free-Electron Lasers, (28 April 2000); doi: 10.1117/12.384251
Show Author Affiliations
Cynthia B. Paschal, Vanderbilt Univ. (United States)
Frank Edward Carroll M.D., Vanderbilt Univ. (United States)
John A. Worrell, Vanderbilt Univ. (United States)
Marcus H. Mendenhall, Vanderbilt Univ. (United States)
Robert H. Traeger, Vanderbilt Univ. (United States)
James W. Waters, Vanderbilt Univ. (United States)
Caryl N. Brzymialkiewicz, Vanderbilt Univ. (United States)
Gwen A. Banks, Vanderbilt Univ. (United States)

Published in SPIE Proceedings Vol. 3925:
Biomedical Applications of Free-Electron Lasers
Glenn S. Edwards; John Clark Sutherland, Editor(s)

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