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Proceedings Paper

Monitoring laser treatment of port wine stains using phase-resolved optical Doppler tomography
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Paper Abstract

We used a novel phase-resolved optical Doppler tomographic (ODT) technique, with very high flow velocity sensitivity and high spatial resolution, to image blood flow in port wine stain (PWS) birthmarks in human skin. The variance of blood flow velocity is used to locate the PWS vessels in addition to the regular ODT images. Our device combines an ODT system and laser so that PWS blood flow can be monitored in situ before and after treatment. To our knowledge, this is the first clinical application of ODT to provide a fast semi-quantitative evaluation of the efficacy of PWS laser therapy in situ and in real-time.

Paper Details

Date Published: 28 April 2000
PDF: 6 pages
Proc. SPIE 3915, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV, (28 April 2000); doi: 10.1117/12.384162
Show Author Affiliations
Yonghua Zhao, Beckman Laser Institute and Medical Clinic (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)
Christopher E. Saxer, Beckman Laser Institute and Medical Clinic (United States)
Johannes F. de Boer, Beckman Laser Institute and Medical Clinic (United States)
Boris Majaron, Beckman Laser Institute and Medical Clinic (Slovenia)
Wim Verkruysse, Beckman Laser Institute and Medical Clinic (United States)
J. Stuart Nelson, Beckman Laser Institute and Medical Clinic (United States)


Published in SPIE Proceedings Vol. 3915:
Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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