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Proceedings Paper

In-vivo imaging of blood flow dynamics using color Doppler optical coherence tomography
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Paper Abstract

Noninvasive quantitation of blood flow in the retinal micro circulation may elucidate the progression and treatment of ocular disorders including diabetic retinopathy, age-related degeneration, and glaucoma. Color Doppler optical coherence tomography was recently introduced as a technique allowing simultaneous micron-scale resolution cross-sectional imaging of tissue micro structure and blood flow in the human retina. Here, time-resolved imaging of dynamics of blood flow profiles was performed to measure cardiac pulsatility within retinal vessels. Retinal pulsatility has been shown to decrease throughout the progression of diabetic retinopathy.

Paper Details

Date Published: 28 April 2000
PDF: 6 pages
Proc. SPIE 3915, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV, (28 April 2000); doi: 10.1117/12.384146
Show Author Affiliations
Siavash Yazdanfar, Case Western Reserve Univ. (United States)
Andrew M. Rollins, Case Western Reserve Univ. (United States)
Joseph A. Izatt, Case Western Reserve Univ. (United States)


Published in SPIE Proceedings Vol. 3915:
Coherence Domain Optical Methods in Biomedical Science and Clinical Applications IV
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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