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Proceedings Paper

Probing biological processes using a multifunction "molecular radar"
Author(s): Hui Ma; L. Jin; Chunyang Zhang; Yao Ding; D. Y. Chen
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Paper Abstract

Molecular Radar represents techniques capable of probing in real time biological processes in living samples. Compared to biochemistry techniques, MR focuses on spatial and temporal features of the process. It also integrates different types of measurements in order to interrogate a complicated biological system from different perspectives and to reveal correlation among the measured parameters. Based on a two-photon fluorescence microscope, we are developing a MR with fluorescence imaging and fluorescence correlation spectroscopy functions. Using the system, we obtained free calcium ion response in a transmembrane signal transduction study. In a different effort, the system is being used to obtain autofluorescence of elastin in rat aorta.

Paper Details

Date Published: 21 April 2000
PDF: 5 pages
Proc. SPIE 3922, Scanning and Force Microscopies for Biomedical Applications II, (21 April 2000); doi: 10.1117/12.383344
Show Author Affiliations
Hui Ma, Tsinghua Univ. (China)
L. Jin, Tsinghua Univ. (China)
Chunyang Zhang, Tsinghua Univ. (China)
Yao Ding, Tsinghua Univ. (China)
D. Y. Chen, Tsinghua Univ. (China)

Published in SPIE Proceedings Vol. 3922:
Scanning and Force Microscopies for Biomedical Applications II
Shuming Nie; Eiichi Tamiya; Edward S. Yeung, Editor(s)

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