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Proceedings Paper

Standardizing the MR image intensity scales: making MR intensities have tissue-specific meaning
Author(s): Laszlo G. Nyul; Jayaram K. Udupa
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Paper Abstract

One of the major drawbacks of Magnetic Resonance Imaging (MRI) has been the lack of a standard and quantifiable interpretation of image intensities. Unlike in other modalities such as x-ray computerized tomography, MR images taken for the same patient on the same scanner at different times may appear different from each other due to a variety of scanner-dependent variations, and therefore, the absolute intensity values do not have a fixed meaning. We have devised a two-step method wherein all images can be transformed in such a way that for the same protocol and body region, in the transformed images similar intensities will have similar tissue meaning. Standardized images can be displayed with fixed windows without the need of per case adjustment. More importantly, extraction of quantitative information with fixed windows without the need of per case adjustment. More importantly, extraction of quantitative information about healthy organs or about abnormalities can be considerably simplified. This paper introduces and compares new variants of this standardizing method that can help to overcome some of the problems with the original method.

Paper Details

Date Published: 18 April 2000
PDF: 9 pages
Proc. SPIE 3976, Medical Imaging 2000: Image Display and Visualization, (18 April 2000); doi: 10.1117/12.383076
Show Author Affiliations
Laszlo G. Nyul, Univ. of Pennsylvania (United States)
Jayaram K. Udupa, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 3976:
Medical Imaging 2000: Image Display and Visualization
Seong Ki Mun, Editor(s)

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