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Proceedings Paper

Ultraviolet 2D fluorescence mapping system for the imaging of head and neck tumors
Author(s): Alvin Katz; Howard E. Savage; Fanan Zeng; Jayson Rome; Stimson P. Schantz; Steven A. McCormick; Rubina S. Cocker; Robert R. Alfano
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Paper Abstract

Fluorescence images of ex vivo head and neck tissues were acquired at multiple combinations of emission and excitation wavelengths. The wavelength combinations were selected to map different tissue molecules and structures whose fluorescence signatures have bene used to detect cancer. Fluorescence maps were generated by ratioing fluorescence image intensities. These ratio maps enhanced the ability to recognize regions of tumor and other features in tissues. Histopathological analysis was performed on the tissue samples. Location and shape of features observed in the fluorescence images were correlated with structures observed in histopathology.

Paper Details

Date Published: 19 April 2000
PDF: 4 pages
Proc. SPIE 3917, Optical Biopsy III, (19 April 2000); doi: 10.1117/12.382727
Show Author Affiliations
Alvin Katz, CUNY/City College (United States)
Howard E. Savage, New York Eye and Ear Infirmary (United States)
Fanan Zeng, CUNY/City College (United States)
Jayson Rome, CUNY/City College (United States)
Stimson P. Schantz, New York Eye and Ear Infirmary (United States)
Steven A. McCormick, New York Eye and Ear Infirmary (United States)
Rubina S. Cocker, New York Eye and Ear Infirmary (United States)
Robert R. Alfano, CUNY/City College (United States)


Published in SPIE Proceedings Vol. 3917:
Optical Biopsy III
Robert R. Alfano, Editor(s)

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