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Proceedings Paper

Application of a new electrometric approach to study interaction between biological molecules
Author(s): Nickolaj F. Starodub; Igor P. Goraychuk; Valentyna M. Starodub; Vasyl' V. Il'chenko; Gennagij V. Kuznetsov
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Paper Abstract

In the paper the results about changes of the current- voltage characteristics of the surface-barrier structures (SBS) after the deposition of myoglobin and its specific monoclonal antibodies are presented. It was shown that the SBS structures with ultra-thin films or with ultra-thin layer of the porous silicon are sensitive to the presence of the protein or its specific immune complex on their surfaces. The response of the system depended on the conditions of the specific complex formation. The characteristic optimum of the thickness of Ni film or the layer of the porous silicon was revealed when the changes of the I-V characteristics had a maximum level.

Paper Details

Date Published: 10 April 2000
PDF: 10 pages
Proc. SPIE 4019, Design, Test, Integration, and Packaging of MEMS/MOEMS, (10 April 2000); doi: 10.1117/12.382319
Show Author Affiliations
Nickolaj F. Starodub, A.V. Palladin Institute of Biochemistry (Ukraine)
Igor P. Goraychuk, Kiev Univ. (Ukraine)
Valentyna M. Starodub, A.V. Palladin Institute of Biochemistry (Ukraine)
Vasyl' V. Il'chenko, Kiev Univ. (Ukraine)
Gennagij V. Kuznetsov, Kiev Univ. (Ukraine)


Published in SPIE Proceedings Vol. 4019:
Design, Test, Integration, and Packaging of MEMS/MOEMS
Bernard Courtois; Selden B. Crary; Kaigham J. Gabriel; Jean Michel Karam; Karen W. Markus; Andrew A. O. Tay, Editor(s)

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