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Proceedings Paper

Progress in noninvasive optical diagnostics
Author(s): Omar S. Khalil
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Paper Abstract

It may look odd that a session on noninvasive diagnostks is scheduled as a part of an in— vitro diagnostic instrumentation symposium. Hopefully, NI diagnostics will grow to the extent that we will have several sessions on different aspects of it in future meetings. In this talk I will discuss the general field of non-invasive diagnostics from industry perspective with examples on what are the advances in hemoglobin and glucose measurements. The other two talks in this session will deal with NI optical devices for bilirubin (SpectRx) and Hb/Hct (In-Line Diagnostics) that just achieved regulatory clearance and are ready for the market. A tissue oxygenation photon density waves photometer for tissue oxygenation measurements (ISS Instruments) and a brain oxygen saturation instrument (Hamamatsu) are available commercially for research purposes. It was quite encouraging to see how a novel technology as optical coherence tomography made its way from the research lab to a clinical product for ophthalmic applications, the workshop arranged on this topic was quiet interesting. SPIE had several sessions on the past few years on optical biopsy, laser interaction with tissue, optical coherence tomography, photoacoustics interactions in tissues and photon migrations in tissues. Some of these techniques will eventually find their way to the hospital floor, the ICU and the doctors office. Some of the constant participants in this annual BIOS/SPIE meeting as Chance, Jacques, Gratton, Alfano, Tromberg, Delpy, Fujimuto, Ezzat, and others have laid the scientific foundation of optical diagnostics, practical applications may be soon on the horizon.

Paper Details

Date Published: 11 April 2000
PDF: 13 pages
Proc. SPIE 3913, In-Vitro Diagnostic Instrumentation, (11 April 2000); doi: 10.1117/12.382030
Show Author Affiliations
Omar S. Khalil, Abbott Labs. (United States)


Published in SPIE Proceedings Vol. 3913:
In-Vitro Diagnostic Instrumentation
Gerald E. Cohn, Editor(s)

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