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Proceedings Paper

Progress in development of an imaging system for fluorescence detection of GI tract cancers
Author(s): Jacqueline Hewett; Tracy McKechnie; Wilson Sibbett; Iain Tait; Sami Mohammed; Alfred Cushieri; Valerie Nadeau; Miles J. Padgett
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Paper Abstract

We report on the development of a fluorescence imaging system for early detection of cancers in the GI tract. The system comprises a modified light source, endoscope, camera and associated image processing software. The photosensitizing agent is 5-aminolaevulinic acid, metabolized within the tumor to form protoporphyrin IX that absorbs strongly between 390-410 nm and fluoresces at 635 nm.

Paper Details

Date Published: 29 March 2000
PDF: 5 pages
Proc. SPIE 3909, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX, (29 March 2000); doi: 10.1117/12.379886
Show Author Affiliations
Jacqueline Hewett, Univ. of St. Andrews (United Kingdom)
Tracy McKechnie, Univ. of St. Andrews (United Kingdom)
Wilson Sibbett, Univ. of St. Andrews (United Kingdom)
Iain Tait, Ninewells Hospital and Medical School (United Kingdom)
Sami Mohammed, Ninewells Hospital and Medical School (United Kingdom)
Alfred Cushieri, Ninewells Hospital and Medical School (United Kingdom)
Valerie Nadeau, Univ. of Glasgow (United Kingdom)
Miles J. Padgett, Univ. of Glasglow (United Kingdom)


Published in SPIE Proceedings Vol. 3909:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX
Thomas J. Dougherty, Editor(s)

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