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Proceedings Paper

Characteristics and mechanism of myocardium tissue laser ablation: in-vitro study for transmyocardial laser revascularization
Author(s): Shunichi Sato; Tomoaki Shimada; Makoto Ogura; Miya Ishihara; Tsunenori Arai; Takemi Matsui; Akira Kurita; Minoru Obara; Makoto Kikuchi; Hitoshi Wakisaka; Hiroshi Ashida
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Paper Abstract

To investigate the optimum laser condition for transmyocardial laser revascularization, ablation characteristics of porcine myocardium tissue have been measured in vitro in the spectral region from UV to near IR (230 - 1064 nm). In experiments, a nanosecond, tunable optical parametric oscillator and a Q-switched Nd:YAG laser (the fundamental band and its 2nd, 3rd, and 4th harmonics) were used for ablation. Measurement of ablation hole depth and diameter, and histological analysis with an optical microscopy were performed. It was found that the ablation efficiency increased and the thermal damage threshold of the tissue decreased with decreasing the wavelength. However, at relatively high fluences (approximately 5 J/cm2), unexpected deep ablation was obtained with a 1064-nm laser light, where not thermal but acoustic damage was observed near the walls of the ablation holes. Because intense laser- induced plasma was observed in this case, the shock wave would contribute to removal and/or damage of the tissue.

Paper Details

Date Published: 1 February 2000
PDF: 6 pages
Proc. SPIE 3885, High-Power Laser Ablation II, (1 February 2000); doi: 10.1117/12.376956
Show Author Affiliations
Shunichi Sato, National Defense Medical College (Japan)
Tomoaki Shimada, Keio Univ. (Japan)
Makoto Ogura, Keio Univ. (Japan)
Miya Ishihara, National Defense Medical College (Japan)
Tsunenori Arai, National Defense Medical College (Japan)
Takemi Matsui, National Defense Medical College (Japan)
Akira Kurita, National Defense Medical College (Japan)
Minoru Obara, Keio Univ. (Japan)
Makoto Kikuchi, National Defense Medical College (Japan)
Hitoshi Wakisaka, National Defense Medical College (Japan)
Hiroshi Ashida, National Defense Medical College (Japan)

Published in SPIE Proceedings Vol. 3885:
High-Power Laser Ablation II
Claude R. Phipps; Masayuki Niino, Editor(s)

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