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Proceedings Paper • Open Access

Therapeutic implications of heat-induced lung injury
Author(s): Joe B. Putnam; Sharon L. Thomsen; Michael Siegenthaler

Paper Abstract

The safe and effective use of interstitial thermal therapy (ITT, radiofrequency ablation) for treatment of lung neoplasms was examined in a preclinical model. Lesions were reproducibly created in normal lung parenchyma and were affected by conductive heat loss via air and blood flow and the presence of bronchi. These observations of controlled injury to lung tissue suggest that clinical application would be appropriate and may yield advantages to selected patients with lung neoplasms (lung cancer, pulmonary metastases, etc.) or other pulmonary diseases.

Paper Details

Date Published: 24 January 2000
PDF: 22 pages
Proc. SPIE 10297, Matching the Energy Source to the Clinical Need: A Critical Review, 1029707 (24 January 2000); doi: 10.1117/12.375227
Show Author Affiliations
Joe B. Putnam, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Sharon L. Thomsen, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Michael Siegenthaler, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)


Published in SPIE Proceedings Vol. 10297:
Matching the Energy Source to the Clinical Need: A Critical Review
Thomas P. Ryan, Editor(s)

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