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Proceedings Paper

Issues involved in using sol-gel-derived glasses as platforms for chemical sensing
Author(s): Meagan A. Doody; Gary A. Baker; Siddharth Pandey; Neil J. Bonzagni; Frank V. Bright
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Paper Abstract

Over the past several years our group has been ex;poring the potential of sol-gel-derived glasses as platforms for advanced sensors and biosensors. In this paper we will outline the challenges that are associated with using these xerogels. Toward this end, we discuss recent results from our laboratories on the performance of polyclonal anti- dansyl antibodies sequestered within a series of xerogels. We assess antibody performance by determining the hapten/antibody association constant, the static excitation and emission for the dansyl hapten bound to the antibody combing site, and the excited-state fluorescence anisotropy and intensity decay kinetics for the dansyl/anti-dansyl system within a series of xerogels.

Paper Details

Date Published: 23 November 1999
PDF: 9 pages
Proc. SPIE 3856, Internal Standardization and Calibration Architectures for Chemical Sensors, (23 November 1999); doi: 10.1117/12.371293
Show Author Affiliations
Meagan A. Doody, SUNY/Buffalo (United States)
Gary A. Baker, SUNY/Buffalo (United States)
Siddharth Pandey, SUNY/Buffalo (United States)
Neil J. Bonzagni, SUNY/Buffalo (United States)
Frank V. Bright, SUNY/Buffalo (United States)


Published in SPIE Proceedings Vol. 3856:
Internal Standardization and Calibration Architectures for Chemical Sensors
Ronald E. Shaffer; Radislav A. Potyrailo, Editor(s)

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