Share Email Print
cover

Proceedings Paper

Sequential injection separation and sensing
Author(s): Jay W. Grate; Oleg B. Egorov; Cynthia J. Bruckner-Lea
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Automated microfluidic analysis has historically been carried out by flow injection analysis techniques. Sequential injection analysis represents a more versatile method for automated fluid handling. We have explored the use of sequential injection analysis for performing microcolumn separations. These separations can be used as part of a microanalytical procedure, or for sample preparation. In addition, with detection of retained species on the microcolumn, sequential injection separation represents a technique for sensing. Recently, it has been demonstrated that sequential injection separation can be carried out with renewable separation columns--the beads with interactive surfaces can be delivered to the microcolumn, used for processing the sample, and discarded after each measurement. Delivery of new beads for each measurement provides a method for renewable surface separation and renewable surface sensing. Applications in environmental analysis and bioanalytical chemistry will be presented.

Paper Details

Date Published: 18 November 1999
PDF: 4 pages
Proc. SPIE 3857, Chemical Microsensors and Applications II, (18 November 1999); doi: 10.1117/12.370272
Show Author Affiliations
Jay W. Grate, Pacific Northwest National Lab. (United States)
Oleg B. Egorov, Pacific Northwest National Lab. (United States)
Cynthia J. Bruckner-Lea, Pacific Northwest National Lab. (United States)


Published in SPIE Proceedings Vol. 3857:
Chemical Microsensors and Applications II
Stephanus Buettgenbach, Editor(s)

© SPIE. Terms of Use
Back to Top