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Proceedings Paper

Imaging tissues with a polarized light video camera
Author(s): Steven L. Jacques; Kenneth Lee
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Paper Abstract

A method for imaging the superficial epidermal and papillary dermal layers of the skin is needed when assessing many skin lesions. We have developed an imaging modality using a video camera whose mechanism of contrast is the reflectance of polarized light from superficial skin. By selecting only polarized light to create the image, one rejects the large amount of diffusely reflected light from the deeper dermis. The specular reflectance (or glare) from the skin surface is also avoided in the setup. The resulting polarization picture maximally accents the details of the superficial layer of the skin and removes the effects of melanin pigmentation from the image. For example, freckles simply disappear and nevi lose their dark pigmentation to reveal the details of abnormal cellular growth. An initial clinical study demonstrated that the polarization camera could identify the margins of sclerosing basal cell carcinoma while the eye of the doctor underestimated the margin estimate. The camera identified an 11-mm-diameter lesion while the unaided eye identified a 6-mm-diameter lesion.

Paper Details

Date Published: 17 September 1999
PDF: 7 pages
Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); doi: 10.1117/12.364366
Show Author Affiliations
Steven L. Jacques, Oregon Medical Laser Ctr. (USA) and Oregon Health Sciences Univ. (United States)
Kenneth Lee, Oregon Health Sciences Univ. (United States)


Published in SPIE Proceedings Vol. 3863:
1999 International Conference on Biomedical Optics
Qingming Luo; Britton Chance; Lihong V. Wang; Steven L. Jacques, Editor(s)

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