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Proceedings Paper

Imaging of absorption coefficients and lifetimes in the scattering medium with heterogeneous fluorophore distribution using simply bound constrained minimization
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Paper Abstract

In this contribution, the inverse optical imaging problem is formulated as both simply bound-constrained and unconstrained minimization problems in order to illustrate the reduction in computational time and storage. The Galerkin finite element method is used for the numerical solution of the excitation and emission diffusion equations. The inverse approach employs the truncated Newton method with trust region, and modified automatic reverse differentiation method is used to calculate the gradients thus sped up the computation of the optimization problem.

Paper Details

Date Published: 2 July 1999
PDF: 8 pages
Proc. SPIE 3600, Biomedical Imaging: Reporters, Dyes, and Instrumentation, (2 July 1999); doi: 10.1117/12.351038
Show Author Affiliations
Ranadhir Roy, Purdue Univ. (United States)
Eva Marie Sevick-Muraca, Purdue Univ. (United States)


Published in SPIE Proceedings Vol. 3600:
Biomedical Imaging: Reporters, Dyes, and Instrumentation
Eva Marie Sevick-Muraca; Darryl J. Bornhop; Christopher H. Contag; Eva Marie Sevick-Muraca, Editor(s)

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