Share Email Print
cover

Proceedings Paper

Optical coherence tomography of the rat cochlea: preliminary investigations
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Optical coherence tomography (OCT) was used to image the internal structure of a rat cochlea. Immediately following sacrifice, the temporal bone of a SPrague-Dawley rat was harvested. Axial OCT cross sectional images (over regions of interest, 1 x 1 mm to 2 x 8 mm) were obtained with a spatial resolution of 10-15 μm. The osseous borders of the lateral membranous labyrinth overlying the cochlea and the scala vestibuli, media, and tympani which were well demarcated by the modiolus, Reissner's and the basilar membranes were clearly identified. OCT can be used to image internal structures in the cochlea without violating the osseous labyrinth, and may potentially be used to diagnose inner ear pathology in vivo in both animal and human subjects.

Paper Details

Date Published: 22 June 1999
PDF: 4 pages
Proc. SPIE 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, (22 June 1999); doi: 10.1117/12.350972
Show Author Affiliations
Brian Jet-Fei Wong, Beckman Laser Institute and Medical Clinic and Univ. of California/Irvine (United States)
Johannes F. de Boer, Beckman Laser Institute and Medical Clinic (United States)
Boris Hyle Park, Beckman Laser Institute and Medical Clinic (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)
J. Stuart Nelson, Beckman Laser Institute and Medical Clinic (United States)


Published in SPIE Proceedings Vol. 3590:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX
Kenton W. Gregory; R. Rox Anderson; Kenneth Eugene Bartels; Lawrence S. Bass; Darryl J. Bornhop; C. Gaelyn Garrett; Kenton W. Gregory; Nikiforos Kollias; Harvey Lui; Reza S. Malek; Aaron P. Perlmutter; Hans-Dieter Reidenbach; Lou Reinisch; David S. Robinson; Lloyd P. Tate; Eugene A. Trowers; David S. Robinson; Hans-Dieter Reidenbach; Reza S. Malek; Aaron P. Perlmutter; Lou Reinisch; C. Gaelyn Garrett; Darryl J. Bornhop; Eugene A. Trowers; Kenneth Eugene Bartels; Lloyd P. Tate, Editor(s)

© SPIE. Terms of Use
Back to Top