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Photodynamic therapy of the rabbit bowel and bladder after installation and injection of delta aminolevulinic acid (ALA): uptake of protoporphyrin IX and depth of necrosis
Author(s): Paul A. Merguerian; Jeff L. Pugach; Jane Park; Marja Sepers; Lothar D. Lilge
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Paper Abstract

Management of neurogenic bladders with high pressures and poor compliance often requires surgical enlargement of the bladder utilizing small or large bowel or stomach. The bowel segments usually retain their absorptive and secretory properties causing several complications which include hyperchloremic metabolic acidosis for small and large bowel segments, hypochloremic metabolic alkalosis for stomach segments, increased risk of bacteriuria, stone formation, altered hepatic metabolism and altered drug metabolism. There is also the potential risk of developing cancer at the anastomotic site.

Paper Details

Date Published: 22 June 1999
PDF: 9 pages
Proc. SPIE 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, (22 June 1999); doi: 10.1117/12.350958
Show Author Affiliations
Paul A. Merguerian, Hospital for Sick Children and Ontario Cancer Institute/Univ. of Toronto (Canada)
Jeff L. Pugach, Hospital for Sick Children and Ontario Cancer Institute/Univ. of Toronto (Canada)
Jane Park, Hospital for Sick Children and Ontario Cancer Institute/Univ. of Toronto (Canada)
Marja Sepers, Hospital for Sick Children and Ontario Cancer Institute/Univ. of Toronto (Canada)
Lothar D. Lilge, Hospital for Sick Children and Ontario Cancer Institute/Univ. of Toronto (Canada)


Published in SPIE Proceedings Vol. 3590:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX
Kenton W. Gregory; R. Rox Anderson; David S. Robinson; Reza S. Malek; Lou Reinisch; Darryl J. Bornhop; Kenneth Eugene Bartels; Hans-Dieter Reidenbach; Lloyd P. Tate; C. Gaelyn Garrett; Eugene A. Trowers; Aaron P. Perlmutter; Kenneth Eugene Bartels; Lawrence S. Bass; Darryl J. Bornhop; C. Gaelyn Garrett; Kenton W. Gregory; Nikiforos Kollias; Harvey Lui; Reza S. Malek; Aaron P. Perlmutter; Hans-Dieter Reidenbach; Lou Reinisch; David S. Robinson; Lloyd P. Tate; Eugene A. Trowers, Editor(s)

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