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Proceedings Paper

Experimental verification of the advantage of a 256-element ultrasonic phased array for thermal coagulation of deep seated tissue
Author(s): Douglas R. Daum; Nadine Smith; Nathan McDannold; Kullervo H. Hynynen
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Paper Abstract

A 256 element ultrasonic phased array was constructed from thermal treatment of deep seated tissue. The 1.1 MHz array had a 10 cm radius of curvature and a 12 cm diameter. The elements formed a planar projection grid of 0.65 X 0.65 cm2 such that the focal range of the array was approximately +/- 1 cm from the natural focus of the array both in the focal plane and +/- 2 cm along the array axis. The array was driven with phased continuous wave signals to both shift individual foci and to create multiple focus patterns. The goals of this study were to demonstrate that an array with many elements has the ability to coagulate large volumes of deep seated tissue in a single sonication and to experimentally compare the in vivo thermal measurements of large focal volume sonications to those predicted in a simple simulation model. It was found that the array could coagulate thigh muscle volumes of 3 - 5 cm3 in a twenty second sonication.

Paper Details

Date Published: 21 June 1999
PDF: 10 pages
Proc. SPIE 3664, Medical Imaging 1999: Ultrasonic Transducer Engineering, (21 June 1999); doi: 10.1117/12.350667
Show Author Affiliations
Douglas R. Daum, Brigham and Womens Hospital and Harvard/MIT Div. of Health Science and Technology (United States)
Nadine Smith, Brigham and Womens Hospital (United States)
Nathan McDannold, Brigham and Womens Hospital and Tufts Univ. (United States)
Kullervo H. Hynynen, Brigham and Womens Hospital (United States)


Published in SPIE Proceedings Vol. 3664:
Medical Imaging 1999: Ultrasonic Transducer Engineering
K. Kirk Shung, Editor(s)

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