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Proceedings Paper

Structural change following glaucoma surgery. I. Mapping the aqueous outflow pathways in the normal rabbit eye
Author(s): Pascal F. Chapon; Naoyuki Nakagawa; Hassan Tahi; Francisco Fantes; Philippe Sourdille M.D.; Jean-Marie A. Parel
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Paper Abstract

Glaucoma procedures tend to induce ocular hypotony. Seeking to determine the aqueous outflow pathway, we investigated casting the outflow network by in vivo injection of a polymer in the anterior chamber. Poly(methyl methacrylate) (PMMA) casts of cilioscleral sinus and aqueous veins were made by injecting a mixture of methyl methacrylate, initiator, promoter and blue ink, through the limbus, in the anterior chamber of a anesthetized rabbit. The transfer of PMMA from the cilioscleral sinus of the rabbit eye to the aqueous veins was shown. The anterior chamber and the cilioscleral sinus casts were colored in blue but the aqueous veins casts were transparent due to the filtering effect of the Meshwork discriminating the ink penetration in the aqueous veins. This technique will be useful to help understanding the role-played by the aqueous veins after glaucoma surgery, or after implantation of devices designed to reduce intraocular pressure.

Paper Details

Date Published: 18 June 1999
PDF: 7 pages
Proc. SPIE 3591, Ophthalmic Technologies IX, (18 June 1999); doi: 10.1117/12.350614
Show Author Affiliations
Pascal F. Chapon, Univ. of Miami School of Medicine (France)
Naoyuki Nakagawa, Univ. of Miami School of Medicine/Bascom Palmer Eye Institute and Fukuoka Univ. (Japan)
Hassan Tahi, Univ. of Miami School of Medicine/Bascom Palmer Eye Institute and Univ of Liege (United States)
Francisco Fantes, Univ. of Miami School of Medicine/Bascom Palmer Eye Institute (United States)
Philippe Sourdille M.D., Clinic Sourdille (France)
Jean-Marie A. Parel, Univ. of Miami School of Medicine and College of Engineering, Univ. of Liege (Belgium), (United States)

Published in SPIE Proceedings Vol. 3591:
Ophthalmic Technologies IX
Bruce E. Stuck; Pascal O. Rol; Michael Belkin M.D.; Karen Margaret Joos M.D.; Fabrice Manns; Bruce E. Stuck; Michael Belkin M.D., Editor(s)

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