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Proceedings Paper

Time-resolved reflectance spectroscopy in tissues
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Paper Abstract

A system for the measurement of absorption and scattering spectra of turbid media in a wide spectral range based on time-resolved reflectance spectroscopy is described. The system operates with tunable mode-locked lasers, and an electronic chain for time-correlated single-photon counting. Laser tuning and optimization, acquisition, and data analysis are fully automated so as to allow in vivo spectroscopy of human tissues within a reasonable measurement time. Absorption and transport scattering spectra were acquired from 610 nm up to 1010 nm every 5 nm on different tissues of healthy volunteers. Examples of the female breast as well as of the human forearm and abdomen are presented, showing a high inter- subject variability. Finally, the measured absorption and scattering values are used to calculate the penetration depth of light in the same tissues.

Paper Details

Date Published: 14 June 1999
PDF: 5 pages
Proc. SPIE 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, (14 June 1999); doi: 10.1117/12.350038
Show Author Affiliations
Rinaldo Cubeddu, INFM and Politecnico di Milano (Italy)
Antonio Pifferi, INFM and Politecnico di Milano (Italy)
Paola Taroni, INFM and Politecnico di Milano (Italy)
Alessandro Torricelli, INFM and Politecnico di Milano (Italy)
Gianluca Valentini, INFM and Politecnico di Milano (Italy)


Published in SPIE Proceedings Vol. 3601:
Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical
Steven L. Jacques; David H. Sliney; Gerhard J. Mueller; Gerhard J. Mueller; Andre Roggan; Andre Roggan; David H. Sliney, Editor(s)

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