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Proceedings Paper

New approach for quantitative analysis of myocardial perfusion with magnetic resonance first-pass bolus imaging
Author(s): Helmut Oswald; Bernd Schnackenburg; Axel Bornstedt; Michael Gross; Nidal Al-Saadi; Eicke Nagel; Eckart Fleck
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Paper Abstract

Myocardial perfusion reserve can be noninvasively assessed with cardiovascular magnetic resonance. With magnetic resonance (MR) multislice dynamic imaging techniques it is possible to acquire the complete heart during the first pass of a contrast agent bolus. For diagnostic reasons an important question is to obtain quantitative parameters of the perfusion of the myocardium. We developed a model for the analysis of the contrast agent bolus pass in the myocardium and established a process for the complete task, which will support a routine clinical use delivering these quantitative parameters in a reproducible way. To evaluate the analysis in a collective of patients with single vessel disease and without significant coronary artery disease the signal intensity curves of the first pass of a gadolinium-DTPA bolus injected via a central vein were estimated before and after dipyridamole infusion.

Paper Details

Date Published: 20 May 1999
PDF: 9 pages
Proc. SPIE 3660, Medical Imaging 1999: Physiology and Function from Multidimensional Images, (20 May 1999); doi: 10.1117/12.349617
Show Author Affiliations
Helmut Oswald, Deutsches Herzzentrum Berlin und Charite (Switzerland)
Bernd Schnackenburg, Philips Medical Systems (Germany)
Axel Bornstedt, Deutsches Herzzentrum Berlin und Charite (Germany)
Michael Gross, Deutsches Herzzentrum Berlin und Charite (Germany)
Nidal Al-Saadi, Deutsches Herzzentrum Berlin und Charite (Germany)
Eicke Nagel, Deutsches Herzzentrum Berlin und Charite (Germany)
Eckart Fleck, Deutsches Herzzentrum Berlin und Charite (Germany)


Published in SPIE Proceedings Vol. 3660:
Medical Imaging 1999: Physiology and Function from Multidimensional Images
Chin-Tu Chen; Anne V. Clough, Editor(s)

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