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Proceedings Paper

Improved bolus localization for videodensitometry
Author(s): Robert A. Close; Simon D. Shpilfoygel; Reza Jahan; Gary R. Duckwiler; Daniel J. Valentino
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Paper Abstract

Videodensitometric measurement of blood flow requires injection of spatially varying contrast density with minimal perturbation of the flow. Constant injection does not yield sufficient spatial gradients for flow measurement during peak flow and diastole, whereas pulsed injection superposes a time- varying perturbation on the measured flow. In order to avoid these drawbacks, we propose to pre-load the catheter injection tubing with spatially varying contrast density. This allows us to generate spatially localized contrast profiles in phantoms and to inject temporally varying contrast profiles in vivo without pulsatile injection. In phantom experiments we obtain better spatial localization of bolus using pre-loading than by pulsed injection of pure contrast material. Preliminary results indicate improvement in accuracy of blood flow measurements using pre-loaded bolus.

Paper Details

Date Published: 20 May 1999
PDF: 5 pages
Proc. SPIE 3660, Medical Imaging 1999: Physiology and Function from Multidimensional Images, (20 May 1999); doi: 10.1117/12.349615
Show Author Affiliations
Robert A. Close, Cedars-Sinai Medical Ctr. (United States)
Simon D. Shpilfoygel, Univ. of California/Los Angeles (United States)
Reza Jahan, Univ. of California/Los Angeles (United States)
Gary R. Duckwiler, Univ. of California/Los Angeles (United States)
Daniel J. Valentino, Univ. of California/Los Angeles (United States)


Published in SPIE Proceedings Vol. 3660:
Medical Imaging 1999: Physiology and Function from Multidimensional Images
Chin-Tu Chen; Anne V. Clough, Editor(s)

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